INBDE (Integrated National Board Dental Examination) Practice Exam

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Study for the Integrated National Board Dental Examination with engaging quizzes and detailed multiple-choice questions. Each question comes with hints and explanations to ensure you grasp essential concepts. Prepare effectively for your dental career!

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P. gingivalis produces which enzyme that is a protease cleaving host proteins?

Hyaluronidase
Collagenase
Gingipain
Leukotoxin

The correct answer is: Gingipain

P. gingivalis is a key pathogen in the development of periodontal disease, and one of its virulence factors is the production of gingipains. Gingipains are a type of protease enzyme that play a crucial role in cleaving host proteins, leading to tissue destruction and inflammation in the periodontal tissues. Hyaluronidase is an enzyme that degrades hyaluronic acid, collagenase targets collagen, and leukotoxin is a toxin that targets leukocytes, none of which directly cleave host proteins as effectively as gingipains.